"Molecule ChEMBL ID";"Molecule Name";"Molecule Max Phase";"Molecular Weight";"#RO5 Violations";"AlogP";"Compound Key";"Smiles";"Standard Type";"Standard Relation";"Standard Value";"Standard Units";"pChEMBL Value";"Data Validity Comment";"Comment";"Uo Units";"Ligand Efficiency BEI";"Ligand Efficiency LE";"Ligand Efficiency LLE";"Ligand Efficiency SEI";"Potential Duplicate";"Assay ChEMBL ID";"Assay Description";"Assay Type";"BAO Format ID";"BAO Label";"Assay Organism";"Assay Tissue ChEMBL ID";"Assay Tissue Name";"Assay Cell Type";"Assay Subcellular Fraction";"Assay Parameters";"Assay Variant Accession";"Assay Variant Mutation";"Target ChEMBL ID";"Target Name";"Target Organism";"Target Type";"Document ChEMBL ID";"Source ID";"Source Description";"Document Journal";"Document Year";"Cell ChEMBL ID";"Properties";"Action Type";"Standard Text Value"
"CHEMBL5184894";"";"None";"916.22";"3";"5.74";"C-3";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCCC1";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129405";"Antibacterial activity against Streptococcus dysgalactiae incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Streptococcus dysgalactiae";"None";"None";"None";"None";"";"";"";"CHEMBL1075341";"Streptococcus dysgalactiae";"Streptococcus dysgalactiae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129417";"Antibacterial activity against Escherichia coli ATCC 25922 at pH 7.6 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5179714";"";"None";"976.02";"3";"5.80";"A-7";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccc(Br)cc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"32.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5190735";"";"None";"904.16";"2";"3.93";"C-4";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCC(O)CC1";"MIC";"'='";"16.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5199514";"";"None";"897.13";"3";"5.03";"1-23(A-2)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccccc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"4.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129408";"Antibacterial activity against Pseudomonas aeruginosa LTP-3 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Pseudomonas aeruginosa";"None";"None";"None";"None";"";"";"";"CHEMBL348";"Pseudomonas aeruginosa";"Pseudomonas aeruginosa";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"4.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129424";"Antibacterial activity against Staphylococcus aureus ATCC 29213 at pH 6.8 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129426";"Antibacterial activity against Staphylococcus aureus ATCC 29213 at pH 7.2 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5191683";"";"None";"916.22";"3";"5.45";"C-5";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CC(C)CC(C)C1";"MIC";"'='";"16.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5206160";"";"None";"821.03";"2";"3.46";"1-22(A-1)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"4.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129407";"Antibacterial activity against Escherichia coli incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5189248";"";"None";"848.10";"2";"4.03";"1-25(C-6)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(C)C";"MIC";"'='";"0.25";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129399";"Antibacterial activity against Staphylococcus aureus incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5204817";"";"None";"899.10";"2";"3.82";"A-22";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2cncnc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"32.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5188035";"";"None";"925.18";"3";"5.60";"A-14";"CCc1ccc(CN(CC[C@H]2C[C@@H](C)C(=O)/C=C/C(C)=C/[C@H](CO)[C@@H](CC)OC(=O)C[C@@H](O)[C@H](C)[C@H]2O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)Cc2cn(-c3cnc4ccccc4c3)nn2)cc1";"MIC";"'='";"16.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5191707";"";"None";"904.21";"3";"5.59";"C-8";"CCCN(CCC)C[C@H]1/C=C(C)/C=C/C(=O)[C@H](C)C[C@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)[C@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](C)[C@H](O)CC(=O)O[C@@H]1CC";"MIC";"'='";"8.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5196619";"";"None";"898.11";"2";"4.43";"A-15";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccncc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"32.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5199514";"";"None";"897.13";"3";"5.03";"1-23(A-2)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccccc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"8.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5191707";"";"None";"904.21";"3";"5.59";"C-8";"CCCN(CCC)C[C@H]1/C=C(C)/C=C/C(=O)[C@H](C)C[C@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)[C@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](C)[C@H](O)CC(=O)O[C@@H]1CC";"MIC";"'='";"4.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5189248";"";"None";"848.10";"2";"4.03";"1-25(C-6)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(C)C";"MIC";"'='";"2.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129407";"Antibacterial activity against Escherichia coli incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"449.33";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129457";"Genotoxicity in Salmonella typhimurium TA102 assessed as number of revertants at 1x10^-3 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 465.33 +/- 18.04 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"456.67";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129458";"Genotoxicity in Salmonella typhimurium TA102 assessed as number of revertants at 2x10^-4 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 465.33 +/- 18.04 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129390";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs using 10^5 CFU/ml bacterial inoculum by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5184894";"";"None";"916.22";"3";"5.74";"C-3";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCCC1";"MIC";"'='";"2.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5204486";"";"None";"903.16";"3";"5.10";"A-18";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2cn(-c3cnc4ccccc4c3)nn2)Cc2cccs2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"16.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5202876";"";"None";"876.15";"2";"4.81";"C-11";"CCCN(C)C[C@H]1/C=C(C)/C=C/C(=O)[C@H](C)C[C@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)[C@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](C)[C@H](O)CC(=O)O[C@@H]1CC";"MIC";"'='";"16.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"";"";"";"";"";"Non-Toxic";"";"";"";"";"";"0";"CHEMBL5129370";"Toxicity in Kunming mouse infected with Staphylococcus aureus ATCC 25923 assessed as normal alveolar size and morphology at 20 to 40 mg/kg, iv measured after 1 hr by hematoxylin and eosin staining based microscopic analysis";"T";"BAO_0000218";"organism-based format";"Mus musculus";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Dose_Lower = 20.0 mg/kg | Dose_Upper = 40.0 mg/kg | Route: IV | TIME = 1.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.125";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129385";"Antibacterial activity against Staphylococcus aureus ATCC 29213 incubated for 16 to 20 hrs using 10^4 CFU/ml bacterial inoculum by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"223.33";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129443";"Genotoxicity in Salmonella typhimurium TA100 assessed as number of revertants at 2x10^-4 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 221.67 +/- 15.57 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5195351";"";"None";"965.12";"3";"6.05";"A-6";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccc(C(F)(F)F)cc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"16.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5208094";"";"None";"930.93";"2";"4.91";"B-1";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CI";"MIC";"'='";"32.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"1.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5184894";"";"None";"916.22";"3";"5.74";"C-3";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCCC1";"MIC";"'='";"1.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5180308";"";"None";"876.15";"2";"4.81";"C-7";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(CC)CC";"MIC";"'='";"1.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129406";"Antibacterial activity against Staphylococcus chromogenes incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus chromogenes";"None";"None";"None";"None";"";"";"";"CHEMBL5209647";"Staphylococcus chromogenes";"Staphylococcus chromogenes";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"32.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129423";"Antibacterial activity against Staphylococcus aureus ATCC 29213 at pH 6.6 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.25";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129438";"Antibacterial activity against Staphylococcus aureus ATCC 29213 at pH 8.6 incubated for 16 to 20 hrs in absence of foetal bovine serum by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"162.0";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129449";"Genotoxicity in Salmonella typhimurium TA100 assessed as number of revertants at 4x10^-5 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 204.33 +/- 8.14 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"449.33";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129453";"Genotoxicity in Salmonella typhimurium TA102 assessed as number of revertants at 2x10^-4 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 386.67 +/- 23.44 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"6.33";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129464";"Genotoxicity in Salmonella typhimurium TA1535 assessed as number of revertants at 4x10^-5 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 14.33 +/- 0.58 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"11.0";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129466";"Genotoxicity in Salmonella typhimurium TA1535 assessed as number of revertants at 1x10^-3 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 15.33 +/- 2.52 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"15.67";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129476";"Genotoxicity in Salmonella typhimurium TA1537 assessed as number of revertants at 1x10^-3 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 20 +/- 5 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.25";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129399";"Antibacterial activity against Staphylococcus aureus incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129408";"Antibacterial activity against Pseudomonas aeruginosa LTP-3 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Pseudomonas aeruginosa";"None";"None";"None";"None";"";"";"";"CHEMBL348";"Pseudomonas aeruginosa";"Pseudomonas aeruginosa";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5206160";"";"None";"821.03";"2";"3.46";"1-22(A-1)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"2.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5204817";"";"None";"899.10";"2";"3.82";"A-22";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2cncnc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"32.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5209459";"";"None";"932.26";"3";"6.37";"C-9";"CCCCN(CCCC)C[C@H]1/C=C(C)/C=C/C(=O)[C@H](C)C[C@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)[C@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](C)[C@H](O)CC(=O)O[C@@H]1CC";"MIC";"'='";"8.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5176998";"";"None";"911.15";"3";"5.34";"A-13";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccc(C)cc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.25";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129428";"Antibacterial activity against Staphylococcus aureus ATCC 29213 at pH 7.6 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5169799";"";"None";"888.16";"2";"4.96";"1-24(C-1)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCC1";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5199384";"";"None";"887.09";"2";"4.63";"A-4";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2cn(-c3cnc4ccccc4c3)nn2)Cc2ccco2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"32.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"4.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129392";"Antibacterial activity against Escherichia coli ATCC 25922 at pH 7 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5190735";"";"None";"904.16";"2";"3.93";"C-4";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCC(O)CC1";"MIC";"'='";"16.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5180308";"";"None";"876.15";"2";"4.81";"C-7";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(CC)CC";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129399";"Antibacterial activity against Staphylococcus aureus incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"449.33";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129461";"Genotoxicity in Salmonella typhimurium TA102 assessed as number of revertants at 1.6x10^-6 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 465.33 +/- 18.04 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"12.67";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129467";"Genotoxicity in Salmonella typhimurium TA1535 assessed as number of revertants at 2x10^-4 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 15.33 +/- 2.52 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5172132";"";"None";"917.11";"2";"4.12";"A-17";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2cn(-c3cnc4ccccc4c3)nn2)Cc2ccc(CO)o2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"32.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5172132";"";"None";"917.11";"2";"4.12";"A-17";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2cn(-c3cnc4ccccc4c3)nn2)Cc2ccc(CO)o2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"32.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5189248";"";"None";"848.10";"2";"4.03";"1-25(C-6)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(C)C";"MIC";"'='";"1.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129404";"Antibacterial activity against Enterococcus faecium incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Enterococcus faecium";"None";"None";"None";"None";"";"";"";"CHEMBL357";"Enterococcus faecium";"Enterococcus faecium";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5169799";"";"None";"888.16";"2";"4.96";"1-24(C-1)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCC1";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129406";"Antibacterial activity against Staphylococcus chromogenes incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus chromogenes";"None";"None";"None";"None";"";"";"";"CHEMBL5209647";"Staphylococcus chromogenes";"Staphylococcus chromogenes";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5199514";"";"None";"897.13";"3";"5.03";"1-23(A-2)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccccc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"0.25";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5191707";"";"None";"904.21";"3";"5.59";"C-8";"CCCN(CCC)C[C@H]1/C=C(C)/C=C/C(=O)[C@H](C)C[C@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)[C@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](C)[C@H](O)CC(=O)O[C@@H]1CC";"MIC";"'='";"0.25";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5196619";"";"None";"898.11";"2";"4.43";"A-15";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccncc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"32.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5177785";"";"None";"876.15";"2";"4.81";"C-12";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(C)C(C)C";"MIC";"'='";"16.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"62.33";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129366";"Genotoxicity in Salmonella typhimurium TA98 assessed as number of revertants at 4x10^-5 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 57.33 +/- 3.06 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"";"";"";"";"";"Non-Toxic";"";"";"";"";"";"0";"CHEMBL5129375";"Toxicity in Kunming mouse infected with Staphylococcus aureus ATCC 25923 assessed as appearance of pink and spongy lungs at 20 to 40 mg/kg, iv measured after 1 hr by hematoxylin and eosin staining based microscopic analysis";"T";"BAO_0000218";"organism-based format";"Mus musculus";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Dose_Lower = 20.0 mg/kg | Dose_Upper = 40.0 mg/kg | Route: IV | TIME = 1.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Inhibition";"'='";"32.12";"%";"";"";"";"UO_0000187";"";"";"";"";"0";"CHEMBL5129379";"Inhibition of protein synthesis in Escherichia coli ATCC 25922 assessed as reduction in protein content at 4 mg/ml measured upto 12 hrs by microporous enzyme labeling method relative to control";"F";"BAO_0000019";"assay format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL612545";"Unchecked";"";"UNCHECKED";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Dose = 4.0 mg/ml | TIME <= 12.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"";"";"";"";"";"Active";"";"";"";"";"";"0";"CHEMBL5129381";"Induction of drug resistance in Escherichia coli ATCC 25922 assessed as increase in MIC measured after 30 passages by broth microdilution method";"F";"BAO_0000019";"assay format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL612545";"Unchecked";"";"UNCHECKED";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"";"";""
"CHEMBL5208094";"";"None";"930.93";"2";"4.91";"B-1";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CI";"MIC";"'='";"16.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5172132";"";"None";"917.11";"2";"4.12";"A-17";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2cn(-c3cnc4ccccc4c3)nn2)Cc2ccc(CO)o2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"32.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"40.33";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129362";"Genotoxicity in Salmonella typhimurium TA98 assessed as number of revertants at 1x10^-3 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 43.67+/- 7.1 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.25";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129420";"Antibacterial activity against Escherichia coli ATCC 25922 at pH 8.2 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5179450";"";"None";"862.13";"2";"4.42";"C-10";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(C)CC";"MIC";"'='";"8.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"418.0";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129452";"Genotoxicity in Salmonella typhimurium TA102 assessed as number of revertants at 1x10^-3 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 386.67 +/- 23.44 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.25";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129406";"Antibacterial activity against Staphylococcus chromogenes incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus chromogenes";"None";"None";"None";"None";"";"";"";"CHEMBL5209647";"Staphylococcus chromogenes";"Staphylococcus chromogenes";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5190735";"";"None";"904.16";"2";"3.93";"C-4";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCC(O)CC1";"MIC";"'='";"32.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.125";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129412";"Antibacterial activity against Staphylococcus aureus ATCC 29213 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5191683";"";"None";"916.22";"3";"5.45";"C-5";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CC(C)CC(C)C1";"MIC";"'='";"8.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5172132";"";"None";"917.11";"2";"4.12";"A-17";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2cn(-c3cnc4ccccc4c3)nn2)Cc2ccc(CO)o2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5204817";"";"None";"899.10";"2";"3.82";"A-22";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2cncnc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.125";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5180308";"";"None";"876.15";"2";"4.81";"C-7";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(CC)CC";"MIC";"'='";"0.125";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5209459";"";"None";"932.26";"3";"6.37";"C-9";"CCCCN(CCCC)C[C@H]1/C=C(C)/C=C/C(=O)[C@H](C)C[C@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)[C@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](C)[C@H](O)CC(=O)O[C@@H]1CC";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5177785";"";"None";"876.15";"2";"4.81";"C-12";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(C)C(C)C";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5174513";"";"None";"904.14";"2";"4.49";"A-21";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2cn(-c3cnc4ccccc4c3)nn2)Cc2cncs2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"32.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"4.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5179450";"";"None";"862.13";"2";"4.42";"C-10";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(C)CC";"MIC";"'='";"8.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5184894";"";"None";"916.22";"3";"5.74";"C-3";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCCC1";"MIC";"'='";"2.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129407";"Antibacterial activity against Escherichia coli incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5180308";"";"None";"876.15";"2";"4.81";"C-7";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(CC)CC";"MIC";"'='";"2.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129408";"Antibacterial activity against Pseudomonas aeruginosa LTP-3 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Pseudomonas aeruginosa";"None";"None";"None";"None";"";"";"";"CHEMBL348";"Pseudomonas aeruginosa";"Pseudomonas aeruginosa";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129440";"Antibacterial activity against Staphylococcus aureus ATCC 29213 at pH 8.6 incubated for 16 to 20 hrs in presence of 10% foetal bovine serum by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"425.33";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129455";"Genotoxicity in Salmonella typhimurium TA102 assessed as number of revertants at 8x10^-6 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 386.67 +/- 23.44 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.25";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129382";"Antibacterial activity against Staphylococcus aureus ATCC 29213 incubated for 16 to 20 hrs using 10^7 CFU/ml bacterial inoculum by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5169799";"";"None";"888.16";"2";"4.96";"1-24(C-1)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCC1";"MIC";"'='";"8.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5209459";"";"None";"932.26";"3";"6.37";"C-9";"CCCCN(CCCC)C[C@H]1/C=C(C)/C=C/C(=O)[C@H](C)C[C@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)[C@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](C)[C@H](O)CC(=O)O[C@@H]1CC";"MIC";"'='";"16.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5179450";"";"None";"862.13";"2";"4.42";"C-10";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(C)CC";"MIC";"'='";"8.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5206487";"";"None";"940.20";"3";"5.10";"A-5";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccc(N(C)C)cc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"16.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5176998";"";"None";"911.15";"3";"5.34";"A-13";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccc(C)cc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"16.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5189248";"";"None";"848.10";"2";"4.03";"1-25(C-6)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(C)C";"MIC";"'='";"2.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"15.0";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129480";"Genotoxicity in Salmonella typhimurium TA1537 assessed as number of revertants at 1.6x10^-6 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 20 +/- 5 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5189248";"";"None";"848.10";"2";"4.03";"1-25(C-6)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(C)C";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129406";"Antibacterial activity against Staphylococcus chromogenes incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus chromogenes";"None";"None";"None";"None";"";"";"";"CHEMBL5209647";"Staphylococcus chromogenes";"Staphylococcus chromogenes";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5169799";"";"None";"888.16";"2";"4.96";"1-24(C-1)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCC1";"MIC";"'='";"1.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129408";"Antibacterial activity against Pseudomonas aeruginosa LTP-3 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Pseudomonas aeruginosa";"None";"None";"None";"None";"";"";"";"CHEMBL348";"Pseudomonas aeruginosa";"Pseudomonas aeruginosa";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"13.0";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129465";"Genotoxicity in Salmonella typhimurium TA1535 assessed as number of revertants at 8x10^-6 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 14.33 +/- 0.58 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5204817";"";"None";"899.10";"2";"3.82";"A-22";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2cncnc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"32.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5206487";"";"None";"940.20";"3";"5.10";"A-5";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccc(N(C)C)cc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"0.25";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5208094";"";"None";"930.93";"2";"4.91";"B-1";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CI";"MIC";"'='";"2.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5191683";"";"None";"916.22";"3";"5.45";"C-5";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CC(C)CC(C)C1";"MIC";"'='";"2.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5179450";"";"None";"862.13";"2";"4.42";"C-10";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(C)CC";"MIC";"'='";"1.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5176998";"";"None";"911.15";"3";"5.34";"A-13";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccc(C)cc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"16.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5204486";"";"None";"903.16";"3";"5.10";"A-18";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2cn(-c3cnc4ccccc4c3)nn2)Cc2cccs2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"16.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5174513";"";"None";"904.14";"2";"4.49";"A-21";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2cn(-c3cnc4ccccc4c3)nn2)Cc2cncs2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"32.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"";"";"";"";"";"Non-Toxic";"";"";"";"";"";"0";"CHEMBL5129371";"Toxicity in Kunming mouse infected with Staphylococcus aureus ATCC 25923 assessed as intact lung tissue structure at 20 to 40 mg/kg, iv measured after 1 hr by hematoxylin and eosin staining based microscopic analysis";"T";"BAO_0000218";"organism-based format";"Mus musculus";"CHEMBL3638235";"Lung";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Dose_Lower = 20.0 mg/kg | Dose_Upper = 40.0 mg/kg | Route: IV | TIME = 1.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"";"";"";"";"";"Active";"";"";"";"";"";"0";"CHEMBL5129376";"Antibacterial activity against Staphylococcus aureus ATCC 25923 infected in kunming mouse assessed as reduction in viable pathogens at 20 mg/kg, iv measured after 1 hr";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"DOSE = 20.0 mg.kg-1 | Route: IV | TIME = 1.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129387";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs using 10^6 CFU/ml bacterial inoculum by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.25";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129389";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs using 10^4 CFU/ml bacterial inoculum by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"1.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129398";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs in absence of foetal bovine serum by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5206160";"";"None";"821.03";"2";"3.46";"1-22(A-1)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"1.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5199384";"";"None";"887.09";"2";"4.63";"A-4";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2cn(-c3cnc4ccccc4c3)nn2)Cc2ccco2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"0.125";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5174513";"";"None";"904.14";"2";"4.49";"A-21";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2cn(-c3cnc4ccccc4c3)nn2)Cc2cncs2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"1.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"44.67";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129361";"Genotoxicity in Salmonella typhimurium TA98 assessed as number of revertants at 4x10^-5 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 43.67+/- 7.1 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5199514";"";"None";"897.13";"3";"5.03";"1-23(A-2)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccccc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"4.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129404";"Antibacterial activity against Enterococcus faecium incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Enterococcus faecium";"None";"None";"None";"None";"";"";"";"CHEMBL357";"Enterococcus faecium";"Enterococcus faecium";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5206160";"";"None";"821.03";"2";"3.46";"1-22(A-1)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"4.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129408";"Antibacterial activity against Pseudomonas aeruginosa LTP-3 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Pseudomonas aeruginosa";"None";"None";"None";"None";"";"";"";"CHEMBL348";"Pseudomonas aeruginosa";"Pseudomonas aeruginosa";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"1.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129416";"Antibacterial activity against Escherichia coli ATCC 25922 at pH 7.4 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'<='";"0.0625";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129433";"Antibacterial activity against Staphylococcus aureus ATCC 29213 at pH 8.6 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"15.0";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129468";"Genotoxicity in Salmonella typhimurium TA1535 assessed as number of revertants at 4x10^-5 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 15.33 +/- 2.52 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"16.33";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129470";"Genotoxicity in Salmonella typhimurium TA1535 assessed as number of revertants at 1.6x10^-6 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 15.33 +/- 2.52 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"14.67";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129478";"Genotoxicity in Salmonella typhimurium TA1537 assessed as number of revertants at 4x10^-5 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 20 +/- 5 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"6.67";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129481";"Genotoxicity in Salmonella typhimurium TA1535 assessed as number of revertants at 1.6x10^-6 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 14.33 +/- 0.58 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"44.33";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129363";"Genotoxicity in Salmonella typhimurium TA98 assessed as number of revertants at 2x10^-4 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 43.67+/- 7.1 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5184894";"";"None";"916.22";"3";"5.74";"C-3";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCCC1";"MIC";"'='";"2.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129404";"Antibacterial activity against Enterococcus faecium incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Enterococcus faecium";"None";"None";"None";"None";"";"";"";"CHEMBL357";"Enterococcus faecium";"Enterococcus faecium";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"1.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129407";"Antibacterial activity against Escherichia coli incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.25";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129419";"Antibacterial activity against Escherichia coli ATCC 25922 at pH 8 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"15.33";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129471";"Genotoxicity in Salmonella typhimurium TA1537 assessed as number of revertants at 1x10^-3 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 22.67 +/- 2.52 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5176998";"";"None";"911.15";"3";"5.34";"A-13";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccc(C)cc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"16.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5204486";"";"None";"903.16";"3";"5.10";"A-18";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2cn(-c3cnc4ccccc4c3)nn2)Cc2cccs2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"32.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5189248";"";"None";"848.10";"2";"4.03";"1-25(C-6)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(C)C";"MIC";"'='";"4.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5208094";"";"None";"930.93";"2";"4.91";"B-1";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CI";"MIC";"'='";"32.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5206160";"";"None";"821.03";"2";"3.46";"1-22(A-1)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129405";"Antibacterial activity against Streptococcus dysgalactiae incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Streptococcus dysgalactiae";"None";"None";"None";"None";"";"";"";"CHEMBL1075341";"Streptococcus dysgalactiae";"Streptococcus dysgalactiae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5180308";"";"None";"876.15";"2";"4.81";"C-7";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(CC)CC";"MIC";"'='";"4.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129407";"Antibacterial activity against Escherichia coli incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"15.67";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129472";"Genotoxicity in Salmonella typhimurium TA1537 assessed as number of revertants at 2x10^-4 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 22.67 +/- 2.52 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"1.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129434";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs in presence of 5% foetal bovine serum by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"61.33";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129367";"Genotoxicity in Salmonella typhimurium TA98 assessed as number of revertants at 2x10^-4 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 57.33 +/- 3.06 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"";"";"";"";"";"Non-Toxic";"";"";"";"";"";"0";"CHEMBL5129368";"Toxicity in Kunming mouse infected with Staphylococcus aureus ATCC 25923 assessed as normal alveolar wall thickness at 20 to 40 mg/kg, iv measured after 1 hr by hematoxylin and eosin staining based microscopic analysis";"T";"BAO_0000218";"organism-based format";"Mus musculus";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Dose_Lower = 20.0 mg/kg | Dose_Upper = 40.0 mg/kg | Route: IV | TIME = 1.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"2.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129425";"Antibacterial activity against Staphylococcus aureus ATCC 29213 at pH 7 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"220.67";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129448";"Genotoxicity in Salmonella typhimurium TA100 assessed as number of revertants at 2x10^-4 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 204.33 +/- 8.14 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"13.67";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129469";"Genotoxicity in Salmonella typhimurium TA1535 assessed as number of revertants at 8x10^-6 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 15.33 +/- 2.52 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5179714";"";"None";"976.02";"3";"5.80";"A-7";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccc(Br)cc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"32.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"15.0";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129477";"Genotoxicity in Salmonella typhimurium TA1537 assessed as number of revertants at 2x10^-4 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 20 +/- 5 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5180308";"";"None";"876.15";"2";"4.81";"C-7";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(CC)CC";"MIC";"'='";"2.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129404";"Antibacterial activity against Enterococcus faecium incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Enterococcus faecium";"None";"None";"None";"None";"";"";"";"CHEMBL357";"Enterococcus faecium";"Enterococcus faecium";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5202876";"";"None";"876.15";"2";"4.81";"C-11";"CCCN(C)C[C@H]1/C=C(C)/C=C/C(=O)[C@H](C)C[C@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)[C@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](C)[C@H](O)CC(=O)O[C@@H]1CC";"MIC";"'='";"8.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5206487";"";"None";"940.20";"3";"5.10";"A-5";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccc(N(C)C)cc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"16.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5199384";"";"None";"887.09";"2";"4.63";"A-4";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2cn(-c3cnc4ccccc4c3)nn2)Cc2ccco2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"16.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5196619";"";"None";"898.11";"2";"4.43";"A-15";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccncc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"32.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5177785";"";"None";"876.15";"2";"4.81";"C-12";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(C)C(C)C";"MIC";"'='";"8.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5199514";"";"None";"897.13";"3";"5.03";"1-23(A-2)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccccc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129405";"Antibacterial activity against Streptococcus dysgalactiae incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Streptococcus dysgalactiae";"None";"None";"None";"None";"";"";"";"CHEMBL1075341";"Streptococcus dysgalactiae";"Streptococcus dysgalactiae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.25";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129421";"Antibacterial activity against Escherichia coli ATCC 25922 at pH 8.4 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'<='";"0.0625";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129431";"Antibacterial activity against Staphylococcus aureus ATCC 29213 at pH 8.2 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5206160";"";"None";"821.03";"2";"3.46";"1-22(A-1)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"8.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5174513";"";"None";"904.14";"2";"4.49";"A-21";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2cn(-c3cnc4ccccc4c3)nn2)Cc2cncs2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"32.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"201.67";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129444";"Genotoxicity in Salmonella typhimurium TA100 assessed as number of revertants at 4x10^-5 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 221.67 +/- 15.57 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"21.33";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129474";"Genotoxicity in Salmonella typhimurium TA1537 assessed as number of revertants at 8x10^-6 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 22.67 +/- 2.52 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5199514";"";"None";"897.13";"3";"5.03";"1-23(A-2)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccccc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129399";"Antibacterial activity against Staphylococcus aureus incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5184894";"";"None";"916.22";"3";"5.74";"C-3";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCCC1";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129399";"Antibacterial activity against Staphylococcus aureus incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5190735";"";"None";"904.16";"2";"3.93";"C-4";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCC(O)CC1";"MIC";"'='";"8.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5202876";"";"None";"876.15";"2";"4.81";"C-11";"CCCN(C)C[C@H]1/C=C(C)/C=C/C(=O)[C@H](C)C[C@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)[C@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](C)[C@H](O)CC(=O)O[C@@H]1CC";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5195351";"";"None";"965.12";"3";"6.05";"A-6";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccc(C(F)(F)F)cc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"8.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5169799";"";"None";"888.16";"2";"4.96";"1-24(C-1)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCC1";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129405";"Antibacterial activity against Streptococcus dysgalactiae incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Streptococcus dysgalactiae";"None";"None";"None";"None";"";"";"";"CHEMBL1075341";"Streptococcus dysgalactiae";"Streptococcus dysgalactiae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"162.67";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129451";"Genotoxicity in Salmonella typhimurium TA100 assessed as number of revertants at 1.6x10^-6 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 204.33 +/- 8.14 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5184894";"";"None";"916.22";"3";"5.74";"C-3";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCCC1";"MIC";"'='";"1.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129406";"Antibacterial activity against Staphylococcus chromogenes incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus chromogenes";"None";"None";"None";"None";"";"";"";"CHEMBL5209647";"Staphylococcus chromogenes";"Staphylococcus chromogenes";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"60.33";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129396";"Genotoxicity in Salmonella typhimurium TA98 assessed as number of revertants at 1x10^-3 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 57.33 +/- 3.06 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'<='";"0.0625";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129430";"Antibacterial activity against Staphylococcus aureus ATCC 29213 at pH 8 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5206160";"";"None";"821.03";"2";"3.46";"1-22(A-1)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"0.25";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129399";"Antibacterial activity against Staphylococcus aureus incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5179714";"";"None";"976.02";"3";"5.80";"A-7";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccc(Br)cc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"0.125";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5199514";"";"None";"897.13";"3";"5.03";"1-23(A-2)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccccc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"8.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5179714";"";"None";"976.02";"3";"5.80";"A-7";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccc(Br)cc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"8.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5184894";"";"None";"916.22";"3";"5.74";"C-3";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCCC1";"MIC";"'='";"4.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"";"";"";"";"";"Non-Toxic";"";"";"";"";"";"0";"CHEMBL5129372";"Toxicity in Kunming mouse infected with Staphylococcus aureus ATCC 25923 assessed as hyperelastic lung tissue at 20 to 40 mg/kg, iv measured after 1 hr by hematoxylin and eosin staining based microscopic analysis";"T";"BAO_0000218";"organism-based format";"Mus musculus";"CHEMBL3638235";"Lung";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Dose_Lower = 20.0 mg/kg | Dose_Upper = 40.0 mg/kg | Route: IV | TIME = 1.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"";"";"";"";"";"Active";"";"";"";"";"";"0";"CHEMBL5129373";"Antibacterial activity against Staphylococcus aureus ATCC 25923 infected in kunming mouse assessed as reduction in lung congestion at 20 to 40 mg/kg, iv measured after 1 hr by hematoxylin and eosin staining based microscopic analysis";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Dose_Lower = 20.0 mg/kg | Dose_Upper = 40.0 mg/kg | Route: IV | TIME = 1.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"";"";"";"";"";"Active";"";"";"";"";"";"0";"CHEMBL5129378";"Antibacterial activity against Staphylococcus aureus ATCC 25923 infected in kunming mouse assessed as reduction in bacterial load at 20 to 40 mg/kg, iv measured after 1 hr";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Dose_Lower = 20.0 mg/kg | Dose_Upper = 40.0 mg/kg | Route: IV | TIME = 1.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"2.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129395";"Antibacterial activity against Staphylococcus aureus ATCC 29213 at pH 8.6 incubated for 16 to 20 hrs in presence of 50% foetal bovine serum by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5196619";"";"None";"898.11";"2";"4.43";"A-15";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccncc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"0.125";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5206160";"";"None";"821.03";"2";"3.46";"1-22(A-1)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"4.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5169799";"";"None";"888.16";"2";"4.96";"1-24(C-1)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCC1";"MIC";"'='";"2.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5202876";"";"None";"876.15";"2";"4.81";"C-11";"CCCN(C)C[C@H]1/C=C(C)/C=C/C(=O)[C@H](C)C[C@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)[C@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](C)[C@H](O)CC(=O)O[C@@H]1CC";"MIC";"'='";"8.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5206160";"";"None";"821.03";"2";"3.46";"1-22(A-1)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"0.125";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129406";"Antibacterial activity against Staphylococcus chromogenes incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus chromogenes";"None";"None";"None";"None";"";"";"";"CHEMBL5209647";"Staphylococcus chromogenes";"Staphylococcus chromogenes";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.25";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129427";"Antibacterial activity against Staphylococcus aureus ATCC 29213 at pH 7.4 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"433.33";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129459";"Genotoxicity in Salmonella typhimurium TA102 assessed as number of revertants at 4x10^-5 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 465.33 +/- 18.04 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129418";"Antibacterial activity against Escherichia coli ATCC 25922 at pH 7.8 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"174.67";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129447";"Genotoxicity in Salmonella typhimurium TA100 assessed as number of revertants at 1x10^-3 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 204.33 +/- 8.14 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"1.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129404";"Antibacterial activity against Enterococcus faecium incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Enterococcus faecium";"None";"None";"None";"None";"";"";"";"CHEMBL357";"Enterococcus faecium";"Enterococcus faecium";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5199514";"";"None";"897.13";"3";"5.03";"1-23(A-2)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccccc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"8.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129407";"Antibacterial activity against Escherichia coli incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"2.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129435";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs in presence of 10% foetal bovine serum by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"32.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129394";"Antibacterial activity against Escherichia coli ATCC 25922 at pH 6.6 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"1.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129397";"Antibacterial activity against Escherichia coli ATCC 25922 at pH 7.2 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5169799";"";"None";"888.16";"2";"4.96";"1-24(C-1)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCC1";"MIC";"'='";"0.25";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129399";"Antibacterial activity against Staphylococcus aureus incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5195351";"";"None";"965.12";"3";"6.05";"A-6";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccc(C(F)(F)F)cc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"0.25";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5188035";"";"None";"925.18";"3";"5.60";"A-14";"CCc1ccc(CN(CC[C@H]2C[C@@H](C)C(=O)/C=C/C(C)=C/[C@H](CO)[C@@H](CC)OC(=O)C[C@@H](O)[C@H](C)[C@H]2O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)Cc2cn(-c3cnc4ccccc4c3)nn2)cc1";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5199384";"";"None";"887.09";"2";"4.63";"A-4";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2cn(-c3cnc4ccccc4c3)nn2)Cc2ccco2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"8.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5206487";"";"None";"940.20";"3";"5.10";"A-5";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccc(N(C)C)cc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"8.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5177785";"";"None";"876.15";"2";"4.81";"C-12";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(C)C(C)C";"MIC";"'='";"8.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5199514";"";"None";"897.13";"3";"5.03";"1-23(A-2)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccccc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"4.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129406";"Antibacterial activity against Staphylococcus chromogenes incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus chromogenes";"None";"None";"None";"None";"";"";"";"CHEMBL5209647";"Staphylococcus chromogenes";"Staphylococcus chromogenes";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Ratio";"'='";"2.0";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129413";"Ratio of MBC to MIC for Staphylococcus aureus ATCC 29213";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"";"";""
"CHEMBL5180308";"";"None";"876.15";"2";"4.81";"C-7";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(CC)CC";"MIC";"'='";"4.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5180308";"";"None";"876.15";"2";"4.81";"C-7";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(CC)CC";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129405";"Antibacterial activity against Streptococcus dysgalactiae incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Streptococcus dysgalactiae";"None";"None";"None";"None";"";"";"";"CHEMBL1075341";"Streptococcus dysgalactiae";"Streptococcus dysgalactiae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.25";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129422";"Antibacterial activity against Escherichia coli ATCC 25922 at pH 8.6 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'<='";"0.0625";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129429";"Antibacterial activity against Staphylococcus aureus ATCC 29213 at pH 7.8 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"1.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129441";"Antibacterial activity against Staphylococcus aureus ATCC 29213 at pH 8.6 incubated for 16 to 20 hrs in presence of 25% foetal bovine serum by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"466.67";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129460";"Genotoxicity in Salmonella typhimurium TA102 assessed as number of revertants at 8x10^-6 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 465.33 +/- 18.04 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"5.0";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129462";"Genotoxicity in Salmonella typhimurium TA1535 assessed as number of revertants at 1x10^-3 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 14.33 +/- 0.58 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.0625";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129386";"Antibacterial activity against Staphylococcus aureus ATCC 29213 incubated for 16 to 20 hrs using 10^3 CFU/ml bacterial inoculum by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"1.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129388";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs using 10^7 CFU/ml bacterial inoculum by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.25";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129391";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs using 10^3 CFU/ml bacterial inoculum by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5204486";"";"None";"903.16";"3";"5.10";"A-18";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2cn(-c3cnc4ccccc4c3)nn2)Cc2cccs2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"0.125";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5191707";"";"None";"904.21";"3";"5.59";"C-8";"CCCN(CCC)C[C@H]1/C=C(C)/C=C/C(=O)[C@H](C)C[C@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)[C@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](C)[C@H](O)CC(=O)O[C@@H]1CC";"MIC";"'='";"4.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5189248";"";"None";"848.10";"2";"4.03";"1-25(C-6)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(C)C";"MIC";"'='";"2.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129405";"Antibacterial activity against Streptococcus dysgalactiae incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Streptococcus dysgalactiae";"None";"None";"None";"None";"";"";"";"CHEMBL1075341";"Streptococcus dysgalactiae";"Streptococcus dysgalactiae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5169799";"";"None";"888.16";"2";"4.96";"1-24(C-1)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCC1";"MIC";"'='";"2.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5206160";"";"None";"821.03";"2";"3.46";"1-22(A-1)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"2.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129404";"Antibacterial activity against Enterococcus faecium incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Enterococcus faecium";"None";"None";"None";"None";"";"";"";"CHEMBL357";"Enterococcus faecium";"Enterococcus faecium";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5184894";"";"None";"916.22";"3";"5.74";"C-3";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCCC1";"MIC";"'='";"1.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129408";"Antibacterial activity against Pseudomonas aeruginosa LTP-3 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Pseudomonas aeruginosa";"None";"None";"None";"None";"";"";"";"CHEMBL348";"Pseudomonas aeruginosa";"Pseudomonas aeruginosa";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MBC";"'='";"0.25";"ug ml-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129411";"Bactericidal activity against Staphylococcus aureus ATCC 29213 incubated for 20 to 24 hrs by CLSI based analysis";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 20.0 hrs | Time_Upper = 24.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"1.0";"CFU/ml";"";"";"";"";"";"";"";"";"0";"CHEMBL5129414";"Bactericidal activity against Escherichia coli ATCC 25922 assessed as reduction in number of viable bacteria at 4 times MIC measured after 2 hrs by time kill assay (Rvb = 10^4.85 CFU/ml)";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 2.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'<='";"0.0625";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129432";"Antibacterial activity against Staphylococcus aureus ATCC 29213 at pH 8.4 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"157.67";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129446";"Genotoxicity in Salmonella typhimurium TA100 assessed as number of revertants at 1.6x10^-6 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 221.67 +/- 15.57 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"371.33";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129456";"Genotoxicity in Salmonella typhimurium TA102 assessed as number of revertants at 1.6x10^-6 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 386.67 +/- 23.44 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"19.67";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129473";"Genotoxicity in Salmonella typhimurium TA1537 assessed as number of revertants at 4x10^-5 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 22.67 +/- 2.52 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"14.33";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129475";"Genotoxicity in Salmonella typhimurium TA1537 assessed as number of revertants at 1.6x10^-6 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 22.67 +/- 2.52 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"4.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129436";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs in presence of 25% foetal bovine serum by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"4.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129437";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs in presence of 50% foetal bovine serum by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"17.67";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129479";"Genotoxicity in Salmonella typhimurium TA1537 assessed as number of revertants at 8x10^-6 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 20 +/- 5 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"42.33";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129359";"Genotoxicity in Salmonella typhimurium TA98 assessed as number of revertants at 1.6x10^-6 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 43.67+/- 7.1 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"64.33";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129364";"Genotoxicity in Salmonella typhimurium TA98 assessed as number of revertants at 1.6x10^-6 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 57.33 +/- 3.06 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Inhibition";"";"";"%";"";"";"NA";"UO_0000187";"";"";"";"";"0";"CHEMBL5129380";"Inhibition of DNA synthesis in Escherichia coli ATCC 25922 at 4 mg/ml measured upto 12 hrs by DAPI staining based fluorescence microscopic analysis";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Dose = 4.0 mg/ml | TIME <= 12.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.25";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129383";"Antibacterial activity against Staphylococcus aureus ATCC 29213 incubated for 16 to 20 hrs using 10^6 CFU/ml bacterial inoculum by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5189248";"";"None";"848.10";"2";"4.03";"1-25(C-6)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(C)C";"MIC";"'='";"0.25";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5184894";"";"None";"916.22";"3";"5.74";"C-3";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCCC1";"MIC";"'='";"0.125";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129400";"Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5188035";"";"None";"925.18";"3";"5.60";"A-14";"CCc1ccc(CN(CC[C@H]2C[C@@H](C)C(=O)/C=C/C(C)=C/[C@H](CO)[C@@H](CC)OC(=O)C[C@@H](O)[C@H](C)[C@H]2O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)Cc2cn(-c3cnc4ccccc4c3)nn2)cc1";"MIC";"'='";"32.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"45.67";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129360";"Genotoxicity in Salmonella typhimurium TA98 assessed as number of revertants at 8x10^-6 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 43.67+/- 7.1 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"";"";"";"";"";"Non-Toxic";"";"";"";"";"";"0";"CHEMBL5129369";"Toxicity in Kunming mouse infected with Staphylococcus aureus ATCC 25923 assessed as reduction in neutrophils at 20 to 40 mg/kg, iv measured after 1 hr by hematoxylin and eosin staining based microscopic analysis";"T";"BAO_0000218";"organism-based format";"Mus musculus";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Dose_Lower = 20.0 mg/kg | Dose_Upper = 40.0 mg/kg | Route: IV | TIME = 1.0 hr";"";""
"CHEMBL5195351";"";"None";"965.12";"3";"6.05";"A-6";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccc(C(F)(F)F)cc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"32.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5189248";"";"None";"848.10";"2";"4.03";"1-25(C-6)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(C)C";"MIC";"'='";"2.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5180308";"";"None";"876.15";"2";"4.81";"C-7";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(CC)CC";"MIC";"'='";"2.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5188035";"";"None";"925.18";"3";"5.60";"A-14";"CCc1ccc(CN(CC[C@H]2C[C@@H](C)C(=O)/C=C/C(C)=C/[C@H](CO)[C@@H](CC)OC(=O)C[C@@H](O)[C@H](C)[C@H]2O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)Cc2cn(-c3cnc4ccccc4c3)nn2)cc1";"MIC";"'='";"16.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5209459";"";"None";"932.26";"3";"6.37";"C-9";"CCCCN(CCCC)C[C@H]1/C=C(C)/C=C/C(=O)[C@H](C)C[C@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)[C@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](C)[C@H](O)CC(=O)O[C@@H]1CC";"MIC";"'='";"16.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5169799";"";"None";"888.16";"2";"4.96";"1-24(C-1)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCC1";"MIC";"'='";"2.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129407";"Antibacterial activity against Escherichia coli incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.5";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129439";"Antibacterial activity against Staphylococcus aureus ATCC 29213 at pH 8.6 incubated for 16 to 20 hrs in presence of 5% foetal bovine serum by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"231.0";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129442";"Genotoxicity in Salmonella typhimurium TA100 assessed as number of revertants at 1x10^-3 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 221.67 +/- 15.57 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"226.0";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129445";"Genotoxicity in Salmonella typhimurium TA100 assessed as number of revertants at 8x10^-6 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 221.67 +/- 15.57 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.125";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129384";"Antibacterial activity against Staphylococcus aureus ATCC 29213 incubated for 16 to 20 hrs using 10^5 CFU/ml bacterial inoculum by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MBC";"'='";"2.0";"ug ml-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129409";"Bactericidal activity against Escherichia coli ATCC 25922 incubated for 20 to 24 hrs by CLSI based analysis";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 20.0 hrs | Time_Upper = 24.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"0.25";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129405";"Antibacterial activity against Streptococcus dysgalactiae incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Streptococcus dysgalactiae";"None";"None";"None";"None";"";"";"";"CHEMBL1075341";"Streptococcus dysgalactiae";"Streptococcus dysgalactiae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"63.33";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129365";"Genotoxicity in Salmonella typhimurium TA98 assessed as number of revertants at 8x10^-6 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 57.33 +/- 3.06 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Inhibition";"";"";"%";"";"";"NA";"UO_0000187";"";"";"";"";"0";"CHEMBL5129377";"Antibacterial activity against Staphylococcus aureus ATCC 25923 infected in kunming mouse assessed as inhibition of bacterial growth at 10 mg/kg, iv measured after 1 hr";"F";"BAO_0000218";"organism-based format";"Staphylococcus aureus";"None";"None";"None";"None";"";"";"";"CHEMBL352";"Staphylococcus aureus";"Staphylococcus aureus";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"DOSE = 10.0 mg.kg-1 | Route: IV | TIME = 1.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"MIC";"'='";"8.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129393";"Antibacterial activity against Escherichia coli ATCC 25922 at pH 6.8 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5191683";"";"None";"916.22";"3";"5.45";"C-5";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CC(C)CC(C)C1";"MIC";"'='";"8.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129401";"Antibacterial activity against Escherichia coli ATCC 25922 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5169799";"";"None";"888.16";"2";"4.96";"1-24(C-1)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCC1";"MIC";"'='";"1.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129404";"Antibacterial activity against Enterococcus faecium incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Enterococcus faecium";"None";"None";"None";"None";"";"";"";"CHEMBL357";"Enterococcus faecium";"Enterococcus faecium";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Ratio";"'='";"2.0";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129410";"Ratio of MBC to MIC for Escherichia coli ATCC 25922";"F";"BAO_0000218";"organism-based format";"Escherichia coli";"None";"None";"None";"None";"";"";"";"CHEMBL354";"Escherichia coli";"Escherichia coli";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"167.0";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129450";"Genotoxicity in Salmonella typhimurium TA100 assessed as number of revertants at 8x10^-6 mg/plate incubated for 72 hrs in presence of liver S9 fraction by Ames test (Rvb = 204.33 +/- 8.14 No_unit)";"T";"BAO_0000220";"subcellular format";"Salmonella enterica subsp. enterica serovar Typhimurium";"CHEMBL3559723";"Liver";"None";"S9";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"429.33";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129454";"Genotoxicity in Salmonella typhimurium TA102 assessed as number of revertants at 4x10^-5 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 386.67 +/- 23.44 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""
"CHEMBL5199514";"";"None";"897.13";"3";"5.03";"1-23(A-2)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(Cc2ccccc2)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO";"MIC";"'='";"32.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129402";"Antibacterial activity against Cronobacter sakazakii ATCC 29544 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Cronobacter sakazakii";"None";"None";"None";"None";"";"";"";"CHEMBL4523084";"Cronobacter sakazakii";"Cronobacter sakazakii";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5180308";"";"None";"876.15";"2";"4.81";"C-7";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(CC)CC";"MIC";"'='";"1.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129403";"Antibacterial activity against Klebsiella pneumoniae ATCC 13883 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Klebsiella pneumoniae";"None";"None";"None";"None";"";"";"";"CHEMBL350";"Klebsiella pneumoniae";"Klebsiella pneumoniae";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5189248";"";"None";"848.10";"2";"4.03";"1-25(C-6)";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN(C)C";"MIC";"'='";"2.0";"ug.mL-1";"";"";"";"UO_0000274";"";"";"";"";"0";"CHEMBL5129408";"Antibacterial activity against Pseudomonas aeruginosa LTP-3 incubated for 16 to 20 hrs by broth microdilution method";"F";"BAO_0000218";"organism-based format";"Pseudomonas aeruginosa";"None";"None";"None";"None";"";"";"";"CHEMBL348";"Pseudomonas aeruginosa";"Pseudomonas aeruginosa";"ORGANISM";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"Time_Lower = 16.0 hrs | Time_Upper = 20.0 hrs";"";""
"CHEMBL5198466";"";"None";"902.19";"3";"5.35";"C-2";"CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@@H](CCN(C)Cc2cn(-c3cnc4ccccc4c3)nn2)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CN1CCCCCC1";"Activity";"'='";"10.33";"";"";"";"";"";"";"";"";"";"0";"CHEMBL5129463";"Genotoxicity in Salmonella typhimurium TA1535 assessed as number of revertants at 2x10^-4 mg/plate incubated for 72 hrs in absence of liver S9 fraction by Ames test (Rvb = 14.33 +/- 0.58 No_unit)";"T";"BAO_0000019";"assay format";"Salmonella enterica subsp. enterica serovar Typhimurium";"None";"None";"None";"None";"";"";"";"CHEMBL612558";"ADMET";"";"ADMET";"CHEMBL5126592";"1";"Scientific Literature";"Eur J Med Chem";"2022";"None";"TIME = 72.0 hr";"";""