diff --git a/Dockerfile.4.pyautofep b/Dockerfile.4.pyautofep
new file mode 100644
index 0000000..7856abe
--- /dev/null
+++ b/Dockerfile.4.pyautofep
@@ -0,0 +1,23 @@
+# syntax=docker/dockerfile:1.3-labs
+# NOTE: Building this image requires Docker version >= 23.0.
+
+# Stage 1: Build environment
+ARG TAG_VERSION
+ARG BASE
+FROM ${BASE}:${TAG_VERSION} AS build-env
+
+# Install PyAutoFEP
+RUN <<EOT
+#!/bin/bash
+git clone https://github.com/luancarvalhomartins/PyAutoFEP.git
+EOT
+
+# Install AmberTools and Amber
+COPY file/Amber24.tar.bz2 file/AmberTools24.tar.bz2 /root
+RUN <<EOT
+#!/bin/bash
+tar -xjvf Amber24.tar.bz2
+tar -xjvf AmberTools24.tar.bz2
+EOT
+
+# install mmgbsa
\ No newline at end of file
diff --git a/Dockerfile.5.mmgbsa b/Dockerfile.5.mmgbsa
new file mode 100644
index 0000000..e69de29