diff --git a/README.md b/README.md
index d31ce1a..3e16874 100644
--- a/README.md
+++ b/README.md
@@ -116,4 +116,10 @@ docker rm <container_name_or_id>
 docker volume rm basic-example_jupyterhub-data
 docker volume rm docker-jupyterhub_jupyterhub-data
 docker volume rm jupyterhub-user-admin
+```
+
+## 构建
+
+```shell
+docker buildx build -t hotwa/notebook:latest -f Dockerfile.base-notebook . --load
 ```
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diff --git a/spawnerdockerfile/Dockerfile.base-notebook b/spawnerdockerfile/Dockerfile.base-notebook
index d4a5a26..d3a9600 100644
--- a/spawnerdockerfile/Dockerfile.base-notebook
+++ b/spawnerdockerfile/Dockerfile.base-notebook
@@ -124,22 +124,30 @@ ENV MAMBA_ROOT_PREFIX=/home/${CREATE_USER}/mamba
 # add pdb env
 RUN <<EOT
 #!/bin/bash
-mamba create -n pdbfixer_env -c conda-forge pdbfixer openmm pymol-open-source rdkit openbabel ipykernel -y
-mamba run -n pdbfixer_env python -m ipykernel install --user --name="pdbfixer" --display-name="PDBfixer Environment"
-mamba create -n scardock_env -c conda-forge -c bioconda -c pylyzeng vinautil ipykernel -y
-mamba run -n scardock_env python -m ipykernel install --user --name="scardock" --display-name="SCARdock Environment"
-mamba create -n fpocket_env -c conda-forge fpocket ipykernel -y
-mamba run -n fpocket_env python -m ipykernel install --user --name="fpocket" --display-name="fpocket Environment"
-EOT
-
-# SCIplot env
-RUN <<EOT
-#!/bin/bash
+conda create -n pdbfixer_env -c conda-forge pdbfixer openmm pymol-open-source rdkit openbabel ipykernel -y
+conda run -n pdbfixer_env python -m ipykernel install --user --name="pdbfixer" --display-name="PDBfixer Environment"
+conda create -n scardock_env -c conda-forge -c bioconda -c pylyzeng vinautil ipykernel -y
+conda run -n scardock_env python -m ipykernel install --user --name="scardock" --display-name="SCARdock Environment"
+conda create -n fpocket_env -c conda-forge fpocket ipykernel -y
+conda run -n fpocket_env python -m ipykernel install --user --name="fpocket" --display-name="fpocket Environment"
 sudo apt update
 sudo apt install -y texlive-full
-micromamba create -n plot -c conda-forge scienceplots autopep8 python=3 ipykernel pandas numpy matplotlib scipy seaborn orange3 -y
-micromamba run -n plot python -m pip install bamboolib
-micromamba run -n plot python -m ipykernel install --user --name="sciplot" --display-name="SCIPlot Environment"
+conda create -n plot -c conda-forge scienceplots autopep8 python=3 ipykernel pandas numpy matplotlib scipy seaborn orange3 -y
+conda run -n plot python -m pip install bamboolib
+conda run -n plot python -m ipykernel install --user --name="sciplot" --display-name="SCIPlot Environment"
 EOT
 
+# RUN <<EOT
+# #!/bin/bash
+# mamba create -n mixtral_env -c conda-forge ipykernel -y
+# mamba run -n mixtral_env python -m pip install 
+# mamba run -n mixtral_env python -m ipykernel install --user --name="mixtral" --display-name="mixtral Environment"
+# EOT
+
+# # new env
+# RUN <<EOT
+# #!/bin/bash
+
+# EOT
+
 WORKDIR "${HOME}"
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