From 4267bda227fa9092628699b6c951f6e31484e74c Mon Sep 17 00:00:00 2001
From: hotwa <pylyzeng@gmail.com>
Date: Thu, 8 Jan 2026 22:29:37 +0800
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- 新增 frontend 环境：Vue 3 + Vite + Element Plus
- 新增 webbackend 环境：FastAPI
- 更新 README 开发文档

🤖 Generated with [Claude Code](https://claude.com/claude-code)

Co-Authored-By: Claude <noreply@anthropic.com>
---
 README.md |  45 ++-
 pixi.lock | 850 ++++++++++++++++++++++++++++++++++++++++++++++++++++++
 pixi.toml |  39 +++
 3 files changed, 932 insertions(+), 2 deletions(-)

diff --git a/README.md b/README.md
index 86ded8a..e86fc31 100644
--- a/README.md
+++ b/README.md
@@ -220,7 +220,7 @@ external_dbs/bt_toxin/
 ├── db/                    # BLAST index files (required)
 │   ├── bt_toxin.phr
 │   ├── bt_toxin.pin
-│   ├── bt_toxin.psq
+│   ├── bt_toxin.ps
 │   └── ...
 └── seq/                   # Source sequences (optional, for reference)
     └── bt_toxin*.fas
@@ -274,6 +274,41 @@ Common insect orders in predictions:
 
 ## Development
 
+### Frontend Development
+
+The frontend is a Vue 3 + Vite + Element Plus application located in `frontend/`.
+
+```bash
+# Install dependencies
+pixi run fe-install
+
+# Start development server (http://localhost:5173)
+pixi run fe-dev
+
+# Build for production
+pixi run fe-build
+
+# Run unit tests
+pixi run fe-test
+
+# Lint and fix code
+pixi run fe-lint
+```
+
+### Web Backend Development
+
+The web backend is a FastAPI application located in `web/backend/`.
+
+```bash
+# Start development server with hot reload (http://localhost:8000)
+pixi run api-dev
+
+# Run tests
+pixi run api-test
+
+# API documentation available at http://localhost:8000/api/docs (when DEBUG=true)
+```
+
 ### Python Development Environment
 
 For development work outside pixi:
@@ -287,8 +322,14 @@ uv pip install -e .
 ### Running Tests
 
 ```bash
-# Run property-based tests
+# Run property-based tests for pipeline
 pixi run -e pipeline python -m pytest tests/test_pixi_runner.py -v
+
+# Run frontend tests
+pixi run fe-test
+
+# Run backend tests
+pixi run api-test
 ```
 
 ### Project Structure
diff --git a/pixi.lock b/pixi.lock
index 494beee..0f6e91a 100644
--- a/pixi.lock
+++ b/pixi.lock
@@ -425,6 +425,37 @@ environments:
       - conda: https://conda.anaconda.org/conda-forge/linux-64/xz-5.2.6-h166bdaf_0.tar.bz2
       - conda: https://conda.anaconda.org/conda-forge/linux-64/zlib-1.2.13-h4ab18f5_6.conda
       - conda: https://conda.anaconda.org/conda-forge/linux-64/zstd-1.5.6-ha6fb4c9_0.conda
+  frontend:
+    channels:
+    - url: https://conda.anaconda.org/conda-forge/
+    - url: https://conda.anaconda.org/bioconda/
+    - url: https://conda.anaconda.org/bioconda/label/cf201901/
+    options:
+      channel-priority: disabled
+    packages:
+      linux-64:
+      - conda: https://conda.anaconda.org/conda-forge/linux-64/_libgcc_mutex-0.1-conda_forge.tar.bz2
+      - conda: https://conda.anaconda.org/conda-forge/linux-64/_openmp_mutex-4.5-2_gnu.tar.bz2
+      - conda: https://conda.anaconda.org/conda-forge/linux-64/c-ares-1.34.6-hb03c661_0.conda
+      - conda: https://conda.anaconda.org/conda-forge/noarch/ca-certificates-2026.1.4-hbd8a1cb_0.conda
+      - conda: https://conda.anaconda.org/conda-forge/linux-64/icu-75.1-he02047a_0.conda
+      - conda: https://conda.anaconda.org/conda-forge/linux-64/libbrotlicommon-1.2.0-hb03c661_1.conda
+      - conda: https://conda.anaconda.org/conda-forge/linux-64/libbrotlidec-1.2.0-hb03c661_1.conda
+      - conda: https://conda.anaconda.org/conda-forge/linux-64/libbrotlienc-1.2.0-hb03c661_1.conda
+      - conda: https://conda.anaconda.org/conda-forge/linux-64/libev-4.33-hd590300_2.conda
+      - conda: https://conda.anaconda.org/conda-forge/linux-64/libgcc-15.2.0-he0feb66_16.conda
+      - conda: https://conda.anaconda.org/conda-forge/linux-64/libgcc-ng-15.2.0-h69a702a_16.conda
+      - conda: https://conda.anaconda.org/conda-forge/linux-64/libgomp-15.2.0-he0feb66_16.conda
+      - conda: https://conda.anaconda.org/conda-forge/linux-64/libnghttp2-1.67.0-had1ee68_0.conda
+      - conda: https://conda.anaconda.org/conda-forge/linux-64/libsqlite-3.51.1-h0c1763c_1.conda
+      - conda: https://conda.anaconda.org/conda-forge/linux-64/libstdcxx-15.2.0-h934c35e_16.conda
+      - conda: https://conda.anaconda.org/conda-forge/linux-64/libstdcxx-ng-15.2.0-hdf11a46_16.conda
+      - conda: https://conda.anaconda.org/conda-forge/linux-64/libuv-1.51.0-hb03c661_1.conda
+      - conda: https://conda.anaconda.org/conda-forge/linux-64/libzlib-1.3.1-hb9d3cd8_2.conda
+      - conda: https://conda.anaconda.org/conda-forge/linux-64/nodejs-24.12.0-h36edbcc_0.conda
+      - conda: https://conda.anaconda.org/conda-forge/linux-64/openssl-3.6.0-h26f9b46_0.conda
+      - conda: https://conda.anaconda.org/conda-forge/linux-64/pnpm-10.27.0-hcdd682b_0.conda
+      - conda: https://conda.anaconda.org/conda-forge/linux-64/zstd-1.5.7-hb78ec9c_6.conda
   pipeline:
     channels:
     - url: https://conda.anaconda.org/conda-forge/
@@ -575,6 +606,95 @@ environments:
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       - conda: https://conda.anaconda.org/conda-forge/linux-64/zstd-1.5.7-hb78ec9c_6.conda
+  webbackend:
+    channels:
+    - url: https://conda.anaconda.org/conda-forge/
+    - url: https://conda.anaconda.org/bioconda/
+    - url: https://conda.anaconda.org/bioconda/label/cf201901/
+    options:
+      channel-priority: disabled
+    packages:
+      linux-64:
+      - conda: https://conda.anaconda.org/conda-forge/linux-64/_libgcc_mutex-0.1-conda_forge.tar.bz2
+      - conda: https://conda.anaconda.org/conda-forge/linux-64/_openmp_mutex-4.5-2_gnu.tar.bz2
+      - conda: https://conda.anaconda.org/conda-forge/noarch/annotated-doc-0.0.4-pyhcf101f3_0.conda
+      - conda: https://conda.anaconda.org/conda-forge/noarch/annotated-types-0.7.0-pyhd8ed1ab_1.conda
+      - conda: https://conda.anaconda.org/conda-forge/noarch/anyio-4.12.1-pyhcf101f3_0.conda
+      - conda: https://conda.anaconda.org/conda-forge/linux-64/bzip2-1.0.8-hda65f42_8.conda
+      - conda: https://conda.anaconda.org/conda-forge/noarch/ca-certificates-2026.1.4-hbd8a1cb_0.conda
+      - conda: https://conda.anaconda.org/conda-forge/noarch/certifi-2026.1.4-pyhd8ed1ab_0.conda
+      - conda: https://conda.anaconda.org/conda-forge/noarch/click-8.3.1-pyh8f84b5b_1.conda
+      - conda: https://conda.anaconda.org/conda-forge/noarch/colorama-0.4.6-pyhd8ed1ab_1.conda
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@@ -627,6 +747,42 @@ packages:
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   size: 592320
   timestamp: 1666699031168
+- conda: https://conda.anaconda.org/conda-forge/noarch/annotated-doc-0.0.4-pyhcf101f3_0.conda
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+  license_family: MIT
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+  timestamp: 1733247158254
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+  - uvloop >=0.21
+  license: MIT
+  license_family: MIT
+  size: 145175
+  timestamp: 1767719033569
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@@ -837,6 +993,14 @@ packages:
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   size: 63362364
   timestamp: 1633194697988
+- conda: https://conda.anaconda.org/conda-forge/noarch/certifi-2026.1.4-pyhd8ed1ab_0.conda
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   size: 29558
   timestamp: 1617035563913
+- conda: https://conda.anaconda.org/conda-forge/noarch/click-8.3.1-pyh8f84b5b_1.conda
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+  md5: ea8a6c3256897cc31263de9f455e25d9
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+  - python >=3.10
+  - __unix
+  - python
+  license: BSD-3-Clause
+  license_family: BSD
+  size: 97676
+  timestamp: 1764518652276
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@@ -856,6 +1031,15 @@ packages:
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   size: 384703
   timestamp: 1738739696573
+- conda: https://conda.anaconda.org/conda-forge/noarch/colorama-0.4.6-pyhd8ed1ab_1.conda
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+  md5: 962b9857ee8e7018c22f2776ffa0b2d7
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+  - python
+  - __glibc >=2.17,<3.0.a0
+  - libgcc >=14
+  - python_abi 3.14.* *_cp314
+  license: BSD-3-Clause
+  license_family: BSD
+  size: 380425
+  timestamp: 1756476367704
 - conda: https://conda.anaconda.org/bioconda/linux-64/wfa2-lib-2.3.5-h9948957_3.tar.bz2
   sha256: 7f72dd792fb72d80b0b0c49d397b5cb50431c672c88b5a9b3e67fbdda005a60a
   md5: 5b4a5fc5b3aa1727a8956d8807310404
@@ -6506,6 +7346,16 @@ packages:
   license: LGPL-2.1 and GPL-2.0
   size: 418368
   timestamp: 1660346797927
+- conda: https://conda.anaconda.org/conda-forge/linux-64/yaml-0.2.5-h280c20c_3.conda
+  sha256: 6d9ea2f731e284e9316d95fa61869fe7bbba33df7929f82693c121022810f4ad
+  md5: a77f85f77be52ff59391544bfe73390a
+  depends:
+  - libgcc >=14
+  - __glibc >=2.17,<3.0.a0
+  license: MIT
+  license_family: MIT
+  size: 85189
+  timestamp: 1753484064210
 - conda: https://conda.anaconda.org/conda-forge/linux-64/zlib-1.2.13-h4ab18f5_6.conda
   sha256: 534824ea44939f3e59ca8ebb95e3ece6f50f9d2a0e69999fbc692311252ed6ac
   md5: 559d338a4234c2ad6e676f460a093e67
diff --git a/pixi.toml b/pixi.toml
index 2151072..ff5ecfa 100644
--- a/pixi.toml
+++ b/pixi.toml
@@ -24,12 +24,34 @@ pandas = ">=2.0.0"
 matplotlib = ">=3.7.0"
 seaborn = ">=0.12.2"
 
+# =========================
+# frontend 环境：Node.js 前端依赖
+# =========================
+[feature.frontend.dependencies]
+nodejs = ">=20"
+pnpm = ">=10"
+
+# =========================
+# webbackend 环境：FastAPI 后端依赖
+# =========================
+[feature.webbackend.dependencies]
+python = ">=3.11"
+fastapi = "*"
+uvicorn = "*"
+pydantic = "*"
+pydantic-settings = "*"
+python-dotenv = "*"
+httpx = "*"
+pytest = "*"
+
 # =========================
 # 环境定义
 # =========================
 [environments]
 digger = ["digger"]
 pipeline = ["pipeline"]
+frontend = ["frontend"]
+webbackend = ["webbackend"]
 
 # =========================
 # pixi tasks
@@ -41,3 +63,20 @@ pipeline = "python scripts/run_single_fna_pipeline.py"
 digger-only = "python scripts/run_digger_stage.py"
 shotter = "python scripts/bttoxin_shoter.py"
 plot = "python scripts/plot_shotter.py"
+
+# =========================
+# frontend tasks
+# =========================
+[feature.frontend.tasks]
+fe-install = { cmd = "pnpm install", cwd = "frontend" }
+fe-dev = { cmd = "pnpm dev", cwd = "frontend" }
+fe-build = { cmd = "pnpm build", cwd = "frontend" }
+fe-test = { cmd = "pnpm test:unit --run", cwd = "frontend" }
+fe-lint = { cmd = "pnpm lint", cwd = "frontend" }
+
+# =========================
+# webbackend tasks
+# =========================
+[feature.webbackend.tasks]
+api-dev = "uvicorn web.backend.main:app --reload --host 0.0.0.0 --port 8000"
+api-test = "pytest web/backend/ -v"